Community Health Network

Ranked among the nation's most integrated healthcare systems, Community Health Network is Central Indiana's leader in providing convenient access to exceptional healthcare services, where and when patients need them—in hospitals, health pavilions, workplaces, schools and homes.

Explore Community


Physician News

Depression Doubles Stroke Risk in Middle-Aged Women

FRIDAY, May 17 (HealthDay News) -- In middle-aged women, depression is associated with a significantly increased risk of stroke, even after adjustment for lifestyle and physiological variables, according to a study published online May 16 in Stroke.

Caroline A. Jackson, Ph.D., and Gita D. Mishra, Ph.D., from the University of Queensland in Herston, Australia examined the effect of depression on stroke incidence in a cohort of 10,547 women (aged 47 to 52 years), without a history of stroke, participating in the Australian Longitudinal Study on Women's Health, who were surveyed every three years from 1998 to 2010. The Center for Epidemiological Studies Depression scale (shortened version) and antidepressant use in the past month were used to define depression.

The researchers found that 24 percent of participants had depression at each survey and 177 strokes occurred during follow-up. Depression correlated with a significantly increased likelihood of stroke (odds ratio, 2.41). This association was reduced after adjustment for age, socioeconomic status, lifestyle, and physiological factors (odds ratio, 1.94). The correlations were robust to sensitivity analyses that addressed methodological issues.

"Our findings contribute to the currently limited evidence on potential age differences in the association between depression and stroke, and suggest that the effect of depression may be even stronger in younger women," the authors write. "Depression appears to operate only partially through known conventional stroke risk factors, suggesting that other mechanisms may be important."

Full Text (subscription or payment may be required)

Health News Copyright © 2013 HealthDay. All rights reserved.

Health Day

Proud sponsor

  • Indiana Fever
  • Indianapolis Indians
  • Indiana Pacers
  • Ed Carpenter Racing
  • Indy Eleven
  • Indy Fuel

Health and wellness shopping

  • Wellspring Medical at Home for medical supplies and equipment
  • FigLeaf Boutique
  • Jasmine gift shop
  • Wellspring Pharmacy

More about shops