Community Health Network

Ranked among the nation's most integrated healthcare systems, Community Health Network is Central Indiana's leader in providing convenient access to exceptional healthcare services, where and when patients need them—in hospitals, health pavilions, workplaces, schools and homes.

Explore Community

Close
News

June 2013 Briefing - Pathology

Here are what the editors at HealthDay consider to be the most important developments in Pathology for June 2013. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Bipartisan Recommendations Can Strengthen Health System

THURSDAY, June 27 (HealthDay News) -- Leaders of the Bipartisan Policy Center Health Care Cost Containment Initiative have developed a series of recommendations to strengthen the U.S. health care system, according to a sounding board piece published online June 26 in the New England Journal of Medicine.

Full Text

FDA Approves Rixubis for Prophylactic Tx in Hemophilia B

THURSDAY, June 27 (HealthDay News) -- Rixubis (coagulation factor IX recombinant) has been approved by the U.S. Food and Drug Administration to prevent routine bleeding episodes in people aged 16 and older with hemophilia B, the agency said in a news release.

More Information

Radiologists' Performance Consistent on CT Colonography

THURSDAY, June 27 (HealthDay News) -- Performance on adenoma and advanced neoplasia detection is consistent among radiologists at computed tomographic (CT) colonography screening, according to a study published in the July issue of Radiology.

Abstract
Full Text (subscription or payment may be required)

Hospital Teaching Intensity Affects Readmission Rates

WEDNESDAY, June 26 (HealthDay News) -- Hospital teaching intensity significantly affects readmission rates for the most common inpatient diagnoses, particularly for safety-net hospitals, according to a study published in the July issue of Medical Care.

Abstract
Full Text (subscription or payment may be required)

HHS Launches Insurance Marketplace Website, Call Center

WEDNESDAY, June 26 (HealthDay News) -- The U.S. Department of Health and Human Services (HHS) has launched the Health Insurance Marketplace education effort, with a consumer-focused website and a consumer call center, to help Americans prepare for enrollment in the new Health Insurance Marketplace.

HealthCare.gov
More Information

8.5 Million Enrollees to Receive Health Insurance Rebates

WEDNESDAY, June 26 (HealthDay News) -- About 8.5 million enrollees will receive a rebate of about $100 per family as part of the Affordable Care Act "80/20" rule, according to a report published by the U.S. Department of Health and Human Services.

More Information

Gene Mutation Influences Aspirin's Colon Cancer Benefit

TUESDAY, June 25 (HealthDay News) -- Regular aspirin use is associated with a lower risk of developing colorectal cancer, but only cancers without mutations in the BRAF oncogene, according to a study published in the June 26 issue of the Journal of the American Medical Association.

Abstract
Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Anti-Gluten Antibodies Linked to Autism

TUESDAY, June 25 (HealthDay News) -- Children with autism have increased levels of anti-gluten antibodies, particularly if they have gastrointestinal symptoms, according to a study published online June 18 in PLOS ONE.

Full Text

Growing Mismatch in Med School Graduates, GME Places

TUESDAY, June 25 (HealthDay News) -- Although the number of medical school enrollees and graduates is increasing, the number of U.S. graduate medical education (GME) programs has not increased at the same rate, and consequently physician shortages are likely to become more apparent, according to a perspective piece published online June 19 in the New England Journal of Medicine.

Full Text

Drop in HPV Prevalence in 14- to 19-Year Olds in Vaccine Era

TUESDAY, June 25 (HealthDay News) -- The prevalence of vaccine-type human papillomavirus (HPV) among 14- to 19-year old females decreased within four years of introduction of vaccination into routine immunization schedules in late 2006, according to research published online June 19 in the Journal of Infectious Diseases.

Abstract
Full Text (subscription or payment may be required)

Publicly Reported Mortality Predicts Hospital Performance

TUESDAY, June 25 (HealthDay News) -- Hospital performance on publicly reported medical conditions is indicative of overall hospital mortality rates, according to a study published online June 24 in JAMA Internal Medicine.

Abstract
Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

AH: Most Acute Care Costs Not Avoidable for High-Cost Patients

MONDAY, June 24 (HealthDay News) -- For high-cost Medicare beneficiaries, only a small percentage of costs are related to preventable emergency department visits and hospitalizations, according to a study published online June 24 in the Journal of the American Medical Association to coincide with presentation at the Annual Research Meeting of AcademyHealth, held from June 23 to 25 in Baltimore.

Full Text
More Information

USPSTF Endorses HCV Screen for High-Risk, Baby Boomers

MONDAY, June 24 (HealthDay News) -- The U.S. Preventive Services Task Force (USPSTF) recommends screening high-risk individuals for hepatitis C virus (HCV) infection, and recommends a one-time screening for all adults born from 1945 to 1965, according to a recommendation statement published in the June 24 issue of the Annals of Internal Medicine.

Full Text
Editorial

Sexual Dysfunction Linked to CVD in Extreme-Duration T1DM

MONDAY, June 24 (HealthDay News) -- For males who have had type 1 diabetes for at least 50 years, sexual dysfunction is associated with large vessel cardiovascular disease, according to a study published online June 18 in Diabetes Care.

Abstract
Full Text (subscription or payment may be required)

Survival of England's National Health Service Questioned

MONDAY, June 24 (HealthDay News) -- Recent criticism of England's National Health Service (NHS) has called its survival into question, according to a perspective piece published online June 19 in the New England Journal of Medicine.

Full Text

Guide Issued for Tying Primary Care to Regional Organizations

MONDAY, June 24 (HealthDay News) -- The Agency for Healthcare Research and Quality has developed a new guide to help primary care practices to assess readiness for connecting electronic health records (EHRs) to regional health information organizations (RHIOs).

More Information

Mortality Similar for Single and Multiple Primary Melanomas

MONDAY, June 24 (HealthDay News) -- Mortality is similar for patients with single primary melanomas (SPMs) and multiple primary melanomas (MPMs), but relative mortality is considerably higher for patients with thicker SPMs versus thicker MPMs, according to a study published online June 19 in JAMA Dermatology.

Abstract
Full Text (subscription or payment may be required)

AMA Awards Grants for Medical Education Innovation

FRIDAY, June 21 (HealthDay News) -- The American Medical Association (AMA) has awarded funding to 11 U.S. medical schools in response to their proposals regarding educational innovations aimed at transforming how future physicians are trained.

More Information

Gene Patenting Ruling Unlikely to Really Impact Oncology Care

FRIDAY, June 21 (HealthDay News) -- The Supreme Court decision in Association for Molecular Pathology v. Myriad is not likely to have much immediate impact the practice of oncology, according to a special communication published online June 13 in the Journal of Clinical Oncology.

Abstract
Full Text

FDA Approves First Genotyping Test for Hepatitis C

FRIDAY, June 21 (HealthDay News) -- A new test to help doctors identify the genotype of a person's hepatitis C infection has been approved by the U.S. Food and Drug Administration.

More Information

Obesity Is a Disease, Says American Medical Association

THURSDAY, June 20 (HealthDay News) -- The American Medical Association has adopted policy that recognizes obesity as a disease, a step that the association hopes will help focus more attention on treatment and prevention efforts, and that some suggest may lead to greater acceptance by insurance providers to cover treatment.

More Information

HPV Antibodies Signal Higher Risk for Oropharyngeal Cancer

THURSDAY, June 20 (HealthDay News) -- In plasma samples obtained prior to diagnosis, the presence of human papillomavirus (HPV) type 16 E6 antibodies was more likely to be detected in patients with oropharyngeal cancer than in controls, according to research published online June 17 in the Journal of Clinical Oncology.

Abstract
Full Text (subscription or payment may be required)

CMS Implementing Physician Quality Reporting System

THURSDAY, June 20 (HealthDay News) -- To promote the reporting of quality information by eligible professionals, the Physician Quality Reporting System is being implemented, according to a report from the Centers for Medicare & Medicaid Services (CMS).

More Information

Practices Are Not Prepared for Implementation of ICD-10

THURSDAY, June 20 (HealthDay News) -- Physician practices have made little progress in preparing for implementation of the 10th revision of the International Classification of Diseases (ICD-10), according to a report published by the Medical Group Management Association (MGMA).

More Information

Serum miR-21 Putative Biomarker for Colorectal Cancer

THURSDAY, June 20 (HealthDay News) -- The oncogenic microRNA (miRNA) miR-21 is a potential biomarker for detection and prognosis of colorectal cancer (CRC), according to a study published in the June 19 issue of the Journal of the National Cancer Institute.

Abstract
Full Text (subscription or payment may be required)

Person-to-Person Transmission of MERS-CoV Identified

WEDNESDAY, June 19 (HealthDay News) -- Person-to-person transmission of the novel Middle East respiratory syndrome coronavirus (MERS-CoV) has been described in a cluster of health care-associated infections in Saudi Arabia, according to research published online June 19 in the New England Journal of Medicine.

Abstract
Full Text

New Rule Proposes Insurance Program Integrity Guidelines

WEDNESDAY, June 19 (HealthDay News) -- A new proposed rule, which provides program integrity guidelines for Affordable Insurance Exchanges, or Health Insurance Marketplaces (Marketplaces), has been released by the U.S. Department of Health and Human Services (HHS).

More Information

EHR Implementation First Step Toward Quality Improvement

WEDNESDAY, June 19 (HealthDay News) -- Implementation of electronic health records (EHRs) is a first step toward quality improvement and should be accompanied by use of new payment models to allow physicians to see a return on their investments, according to Farzad Mostashari, M.D., of the Office of the National Coordinator for Health Information Technology, who was recently interviewed by the American Academy of Family Physicians.

More Information

Potential of Mobile Remote-Presence Devices Discussed

WEDNESDAY, June 19 (HealthDay News) -- Mobile remote-presence devices have the potential to increase access to and improve delivery of health care in the developed and developing world, according to an innovations report published online June 17 in CMAJ, the Journal of the Canadian Medical Association.

Full Text (subscription or payment may be required)

State-Based Health Care Price Websites Lacking

TUESDAY, June 18 (HealthDay News) -- State-based, patient-oriented websites reporting health care prices need to be improved, according to a research letter published in the June 19 issue of the Journal of the American Medical Association.

Full Text (subscription or payment may be required)

Islet Autoantibodies Predict Type 1 Diabetes Progression

TUESDAY, June 18 (HealthDay News) -- Most children genetically at risk of developing type 1 diabetes will develop the disease if they seroconvert to multiple islet autoantibodies, according to a study published in the June 19 issue of the Journal of the American Medical Association.

Abstract
Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

MRI Screening Identifies Undiagnosed Spinal Infections

TUESDAY, June 18 (HealthDay News) -- About a fifth of patients who have received a spinal injection of fungus-contaminated methylprednisolone but have not sought medical care are likely to be infected, according to a study published in the June 19 issue of the Journal of the American Medical Association.

Abstract
Full Text
Editorial (subscription or payment may be required)

Cognitive Impairment, APOE Linked to Aβ Lipidation State

TUESDAY, June 18 (HealthDay News) -- For older adults, the lipidation state of β-amyloid (Aβ) peptides is associated with cognitive impairment and APOE genotype, and can be modulated by diet, according to a study published online June 17 in JAMA Neurology.

Abstract
Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Racial Discrepancy in Oncologic Outcomes for Low-Risk PCa

TUESDAY, June 18 (HealthDay News) -- Among men with very-low-risk prostate cancer (PCa) who meet criteria for active surveillance but undergo radical prostatectomy, African-American race is associated with poorer outcomes, with higher rates of disease upgrading and adverse pathology, according to a study published online June 17 in the Journal of Clinical Oncology.

Abstract
Full Text

Unauthorized Immigrants Make Up 1.4% U.S. Medical Spending

TUESDAY, June 18 (HealthDay News) -- Unauthorized immigrants have substantially lower health care expenditures than legal residents, naturalized citizens, and U.S. natives, according to a study published online June 12 in Health Affairs.

Abstract
Full Text

About 15 Percent of People Currently Uninsured in U.S.

TUESDAY, June 18 (HealthDay News) -- In 2012, nearly 15 percent of U.S. people of all ages were currently uninsured, according to a data brief published online June 18 by the U.S. Centers for Disease Control and Prevention's National Center for Health Statistics (NCHS).

More Information

FDA Discusses Cybersecurity for Medical Devices, Hospitals

MONDAY, June 17 (HealthDay News) -- Medical device manufacturers and health care facilities should ensure appropriate safeguards are in place to reduce the potential harms that may result from cyberattacks, according to a safety communication issued by the U.S. Food and Drug Administration.

More Information

Oncological Outcomes Similar Despite Timing of Prostatectomy

FRIDAY, June 14 (HealthDay News) -- Outcomes are similar between men with histologically comparable prostate cancer who receive a radical prostatectomy after a period of active surveillance and those with low-risk disease who undergo immediate prostatectomy, according to a study published in the July issue of The Journal of Urology.

Abstract
Full Text (subscription or payment may be required)

EHR Improves Coordination of Care in Hematuria Work-Up

FRIDAY, June 14 (HealthDay News) -- Care coordination, enhanced using an electronic health record system, can reduce the number of health care visits needed for the work-up of hematuria, according to a study published in the July issue of The Journal of Urology.

Abstract
Full Text (subscription or payment may be required)

Mutations in COQ2 Linked to Multiple-System Atrophy

THURSDAY, June 13 (HealthDay News) -- Functionally impaired variants in the COQ2 gene, which encodes the enzyme parahydroxybenzoate-polyprenyl transferase, have been identified in multiplex families with multiple-system atrophy and in patients with sporadic disease, according to a study published online June 12 in the New England Journal of Medicine.

Abstract
Full Text

Survey Examines Physician Satisfaction With EHRs

THURSDAY, June 13 (HealthDay News) -- About three-quarters of physicians report that their practice either has a fully implemented electronic health record (EHR), uses a hospital or corporate EHR, or is in the process of implementing an EHR, according to a technology survey published by Physicians Practice.

More Information

SALL4 Protein Reexpressed in Subset of Patients With HCC

WEDNESDAY, June 12 (HealthDay News) -- The oncofetal protein SALL4 is expressed in a subgroup of patients with hepatocellular carcinoma, with overexpression of proliferative and metastatic genes observed in SALL4-positive hepatocellular carcinomas, according to a study published in the June 13 issue of the New England Journal of Medicine.

Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Autoimmune Disease, Infection Risk Factors for Mood Disorders

WEDNESDAY, June 12 (HealthDay News) -- Autoimmune diseases and infections are independent and synergistic risk factors for mood disorders, according to a study published online June 12 in JAMA Psychiatry.

Abstract
Full Text (subscription or payment may be required)

PCA3 Assay Ups Predictive Accuracy for Repeat Biopsy

WEDNESDAY, June 12 (HealthDay News) -- For men with at least one prior negative biopsy, urinary PCA3 scores, together with serum prostate-specific antigen and other clinical information, improve the prediction accuracy for repeat biopsy outcome, according to a study published in the July issue of The Journal of Urology.

Abstract
Full Text

Risk Down for Deceased-Donor Partial Liver Transplant

WEDNESDAY, June 12 (HealthDay News) -- For young pediatric patients, the risk associated with deceased-donor (DD) partial liver transplantation has decreased over time, according to a study published online May 21 in Liver Transplantation.

Abstract
Full Text (subscription or payment may be required)

Screening Has Not Affected Breast CA Mortality in England

WEDNESDAY, June 12 (HealthDay News) -- Mammographic screening, introduced in England in 1988, has not had a significant impact on breast cancer mortality, according to a study published in the June issue of the Journal of the Royal Society of Medicine.

Abstract
Full Text

Use of EHRs Can Enhance Doc-Patient Communication

WEDNESDAY, June 12 (HealthDay News) -- Electronic health records (EHRs) can be used during clinical encounters to enhance the physician-patient relationship, encouraging communication during the clinical encounter, according to a viewpoint published in the June 12 issue of the Journal of the American Medical Association.

Full Text (subscription or payment may be required)

Inflammatory Biomarkers Up Risk of Exacerbations in COPD

TUESDAY, June 11 (HealthDay News) -- For patients with chronic obstructive pulmonary disease (COPD), including those with milder COPD, elevated levels of inflammatory biomarkers correlate with an increased risk of exacerbations, according to a study published in the June 12 issue of the Journal of the American Medical Association.

Abstract
Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Biomarker May Predict Gestational Diabetes Mellitus

TUESDAY, June 11 (HealthDay News) -- Increased plasma concentrations of soluble (pro)renin receptor during the first trimester of pregnancy may predict the development of gestational diabetes mellitus, according to research published in the June issue of the Journal of Clinical Endocrinology & Metabolism.

Abstract
Full Text (subscription or payment may be required)

Doctors Do Not Spend Enough Time Planning Their Finances

TUESDAY, June 11 (HealthDay News) -- Physicians do not spend enough time reviewing their finances, and half are behind in their retirement planning, according to a report published by the American Medical Association (AMA) Insurance Agency.

More Information

Most Doctors Feel They Are Under-Using Mobile Apps

TUESDAY, June 11 (HealthDay News) -- Most physicians feel they are not maximizing use of mobile applications, and would utilize additional electronic health record (EHR) functionalities if they were available, according to poll conducted by Black Book Market Research.

More Information

Women Being Recruited to Join Specific Cancer Registry

FRIDAY, June 7 (HealthDay News) -- Women, with and without cancer, are being recruited to join a cancer registry in an effort to better understand and more effectively treat cancers that primarily affect women, according to a Cedars-Sinai initiative.

More Information

Biological Sex Trait Influences Melanoma Survival

FRIDAY, June 7 (HealthDay News) -- Melanoma progression and survival seem to be substantially influenced by a biologic sex trait, even in advanced disease, according to research published online May 20 in the Journal of Clinical Oncology.

Abstract
Full Text (subscription or payment may be required)

Heart Disease Overreporting May Skew Hospital Death Statistics

FRIDAY, June 7 (HealthDay News) -- The overreporting of heart disease as the cause of death on patient records is often significant and may mask the true levels of cause-specific mortality needed to shape public health priorities, according to a report published online May 16 in Preventing Chronic Disease.

Full Text

Background MRI Enhancement Up in Premenopausal Breast Cancer

FRIDAY, June 7 (HealthDay News) -- Quantitative measurement of background enhancement (BE) on magnetic resonance imaging (MRI) is significantly higher in premenopausal women with breast cancer compared to postmenopausal women with breast cancer, according to a pilot study published in the June issue of Radiology.

Abstract
Full Text (subscription or payment may be required)

Novel Mutations Identified in Central Precocious Puberty

THURSDAY, June 6 (HealthDay News) -- Mutations in the gene encoding makorin RING-finger protein 3 (MKRN3), which result in a truncated protein or disrupted protein function, have been identified in some families affected by central precocious puberty, according to a study published online June 5 in the New England Journal of Medicine.

Abstract
Full Text
Editorial

Secondhand Smoke Impacts Infants With Family Hx of Atopy

THURSDAY, June 6 (HealthDay News) -- For infants with lower respiratory tract infection (LRTI) with a family history of atopy, secondhand smoke (SHS) exposure is associated with a longer hospital length of stay, according to a study published in the June issue of the Annals of Asthma, Allergy & Immunology.

Abstract
Full Text (subscription or payment may be required)

HHS: Marketplaces Open New Insurance Options for Consumers

THURSDAY, June 6 (HealthDay News) -- Health Insurance Marketplaces, due to be introduced in October 2013, will increase the coverage options for many consumers, according to a memo released by the U.S. Department of Human & Health Services.

More Information

Few Physicians Meeting Meaningful Use in Early 2012

WEDNESDAY, June 5 (HealthDay News) -- In early 2012, few physicians met meaningful use criteria, and using electronic health records (EHRs) for patient panel management was difficult, according to research published in the June 5 issue of the Annals of Internal Medicine.

Full Text (subscription or payment may be required)

CDC: Small Drop in Those With Difficulty Paying Medical Bills

TUESDAY, June 4 (HealthDay News) -- There has been a slight decrease in the percentage of individuals aged younger than 65 years who are in a family with difficulty paying their medical bills, according to a June data brief issued by the U.S. Centers for Disease Control and Prevention's National Center for Health Statistics (NCHS).

More Information

Family Cluster of Middle East Coronavirus Infections ID'd

TUESDAY, June 4 (HealthDay News) -- A family cluster of infections with Middle East respiratory syndrome coronavirus (MERS CoV) has been described in a brief report published online May 29 in the New England Journal of Medicine.

Abstract
Full Text (subscription or payment may be required)

Biomarker Not Linked to Multiple Sclerosis Response

TUESDAY, June 4 (HealthDay News) -- Serum levels of interleukin 17F (IL-17F) during early treatment of multiple sclerosis with interferon beta are not associated with responsiveness to treatment, although levels greater than 200 pg/mL may predict lack of response, according to a study published online June 3 in JAMA Neurology.

Abstract
Full Text (subscription or payment may be required)

Blood Tests As Good As Biopsy for HCV-Related Disease

TUESDAY, June 4 (HealthDay News) -- Compared to a liver biopsy, available blood tests are accurate for diagnosing fibrosis and cirrhosis in patients with hepatitis C virus (HCV), according to a review published in the June 4 issue of the Annals of Internal Medicine.

Full Text (subscription or payment may be required)

Vegetarian Dietary Patterns Tied to Lower All-Cause Death

MONDAY, June 3 (HealthDay News) -- Compared with non-vegetarians, vegetarians have reduced all-cause mortality, according to a study published online June 3 in JAMA Internal Medicine.

Abstract
Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Independent Payment Advisory Board's Future Questioned

MONDAY, June 3 (HealthDay News) -- Established as a part of the efforts of Affordable Care Act (ACA) to contain health care costs, the Independent Payment Advisory Board (IPAB) has been surrounded by controversy, and still has no members, according to a perspective piece published online May 29 in the New England Journal of Medicine.

Full Text

Drug Resistant Cancers Have Alternative Drug Target

MONDAY, June 3 (HealthDay News) -- Cancers that develop resistance to anti-epidermal growth factor receptor (EGFR) treatments often have amplification of the MET gene, which can be targeted by drugs to overcome resistance, according to a study published online June 2 in Cancer Discovery.

Abstract
Full Text (subscription or payment may be required)

Health of Nation Reviewed With Focus on Emergency Care

MONDAY, June 3 (HealthDay News) -- Recent trends in the health of the nation are described, with particular focus on emergency care, in the 36th annual report published by the National Center for Health Statistics (NCHS) and the U.S. Centers for Disease Control and Prevention.

More Information

Copyright © 2013 ScoutNews, LLC. All rights reserved.

Health Day

Proud sponsors

  • Indiana Fever
  • Indianapolis Indians
  • Indiana Pacers
  • Sarah Fisher Hartman Racing
  • Indy Eleven
  • Indy Fuel

Health and wellness shopping

  • Home Health Medical online store for medical supplies and equipment
  • Wellspring Pharmacy
  • FigLeaf Boutique
  • Jasmine gift shop