Community Health Network

Ranked among the nation's most integrated healthcare systems, Community Health Network is Central Indiana's leader in providing convenient access to exceptional healthcare services, where and when patients need them—in hospitals, health pavilions, workplaces, schools and homes.

Explore Community

Close
News

Physician News

Pediatric HIV Antiretroviral Treatment Cardioprotective

TUESDAY, April 23 (HealthDay News) -- HIV-infected children treated with highly active antiretroviral therapy (HAART) have better cardiac function than untreated children, according to a study published online April 22 in JAMA Pediatrics.

Steven E. Lipshultz, M.D., from the University of Miami Leonard M. Miller School of Medicine, and colleagues used linear regression models to compare echocardiographic measures for 325 perinatally HIV-infected children receiving HAART; 189 HIV-exposed but uninfected children; and 70 HIV-infected, mostly HAART-unexposed, children (historical pediatric controls).

The researchers found that the HIV-infected children receiving HAART had significantly lower viral loads, higher CD4 counts, and longer treatment durations compared with the historical controls. The z scores for left ventricle fractional shortening (a measure of cardiac function) were significantly lower for the historical controls compared with the other two groups. HIV-infected children with a lower nadir CD4 percentage and a higher current viral load had significantly worse cardiac function, according to the study.

"Long-term HAART appears to be cardioprotective for HIV-infected children and adolescents," Lipshultz and colleagues conclude.

Abstract
Full Text (subscription or payment may be required)

Health News Copyright © 2013 HealthDay. All rights reserved.

Health Day

Proud sponsors

  • Indiana Fever
  • Indianapolis Indians
  • Indiana Pacers
  • Sarah Fisher Hartman Racing
  • Indy Eleven
  • Indy Fuel

Health and wellness shopping

  • Home Health Medical online store for medical supplies and equipment
  • Wellspring Pharmacy
  • FigLeaf Boutique
  • Jasmine gift shop