Community Health Network

Ranked among the nation's most integrated healthcare systems, Community Health Network is Central Indiana's leader in providing convenient access to exceptional healthcare services, where and when patients need them—in hospitals, health pavilions, workplaces, schools and homes.

Explore Community


Physician News

Lupus Ups Risk of Spontaneous Subarachnoid Hemorrhage

FRIDAY, April 19 (HealthDay News) -- Patients with systemic lupus erythematosus (SLE) have an increased risk of spontaneous subarachnoid hemorrhage (SAH) and increased mortality after SAH, according to a study published in the April issue of Arthritis Care & Research.

Yu-Sheng Chang, M.D., from Shuang Ho Hospital in Taipei, Taiwan, and colleagues conducted a nationwide, population-based study to assess the risk of SAH among patients with SLE. The incidence of SAH was compared in a cohort of 16,967 patients with SLE identified from the Taiwan National Health Insurance (NHI) database and 16,967 randomly selected age- and sex-matched individuals without SLE.

The researchers found that the incidence of SAH was significantly higher in the SLE cohort (incidence rate ratio, 4.84). Compared with all the non-SLE SAH patients identified from the NHI database, the mortality rate after SAH was significantly higher for patients with SLE, despite a younger age (60 versus 38.9 percent). Independent risk factors for new-onset SAH included age (hazard ratio [HR], 1.03); platelet transfusion (HR, 2.75); red blood cell transfusion (HR, 7.11); and a mean daily steroid dose greater than 10 mg prednisolone or equivalent (HR, 4.36).

"In conclusion, our study is the first to demonstrate a higher risk of SAH in SLE patients using a nationwide population data set," the authors write. "Elderly SLE patients and those with a higher mean daily steroid dose and a history of platelet or red blood cell transfusion had a higher risk of developing SAH."

Full Text (subscription or payment may be required)

Health News Copyright © 2013 HealthDay. All rights reserved.

Health Day

Proud sponsor

  • Indiana Fever
  • Indianapolis Indians
  • Indiana Pacers
  • Ed Carpenter Racing
  • Indy Eleven
  • Indy Fuel

Health and wellness shopping

  • Wellspring Medical at Home for medical supplies and equipment
  • FigLeaf Boutique
  • Jasmine gift shop
  • Wellspring Pharmacy

More about shops