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Previous Knee Surgery Ups Risk for TKA at Younger Age

WEDNESDAY, June 25, 2014 (HealthDay News) -- Patients with a history of a previous knee surgery tend to undergo total knee arthroplasty (TKA) at a younger age, a trend particularly seen among men, according to a study published May 21 in The Journal of Bone & Joint Surgery.

Robert H. Brophy, M.D., from Washington University in St. Louis, and colleagues analyzed data from a prospective total joint registry for all participating patients undergoing primary TKA.

The researchers found that of 1,286 patients included in the analysis, 29 percent had a history of knee surgery, with significantly more men (39 percent) than women (24 percent) having a history of knee surgery (P < 0.0001). At time of TKA, patients with previous knee surgery were significantly younger (P < 0.0001) than patients without previous knee surgery. There was no significant difference in age at TKA between the sexes among patients with previous knee surgery. Women who underwent TKA as their first knee surgery were significantly younger (65.4 years versus 69.3 years; P < 0.001) than men. The average time from previous knee surgery to TKA was longer in men than in women (13.1 years versus 9.1 years; P < 0.0001).

"Patients with previous knee surgery undergo total knee arthroplasty at a significantly younger age than patients without previous knee surgery, especially men and patients with a history of ligament reconstruction," the authors write. "Future investigation to identify those at risk for early TKA after knee surgery and to develop methods to delay or to prevent the need for future TKA in these patients is warranted."

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