Written by on 6/16/2014 12:00:00 PM
Ovarian cancer risk decreases in women with the BRCA gene mutations if they have breast-fed, taken birth control pills or had their fallopian tubes tied.
A new review study by University of Pennsylvania researchers looked at 44 different medical studies. Women with the BRCA1 gene mutation that breast fed or had a tubal ligation had a lower risk for ovarian cancer. Those women who use birth control pills and have BRCA1 or BRCA2 gene mutations had lower rates of ovarian cancer.
"Our analysis reveals that heredity is not destiny, and that working with their physicians and counselors, women with BRCA mutations can take proactive steps that may reduce their risk of being diagnosed with ovarian cancer," said lead author Timothy Rebbeck, professor of epidemiology and cancer epidemiology and risk reduction program leader at the Abramson Cancer Center.
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Source: U of Penn news release, pending June 2014 publication, Journal of the National Cancer Institute