Posts in "dr-wafic-elmasri/"
Viewing 1-2 of 2 result(s).

FDA approves DNA test for cervical cancer

Written by Community Health Network on 4/25/2014 11:30:00 AM

Thursday, the FDA approved an HPV DNA test for women ages 25 years or older that could be used as a first-line screening method to determine cervical cancer risk.

The test samples women’s cervical cells and looks for 14 high-risk HPV strains. Developed by Roche, the HPV test looks for the most dangerous strains, HPV 16 and HPV 18, while also searching for signs of the additional strains.

Currently, women are tested for HPV after a their Pap test shows abnormal changes on their cervix, or if a physician gives her a test during a standard appointment. Approval for this test, called cobas, means that this should be used as a primary screening tool for HPV.

"FDA approval of primary HPV screening means we can use the HPV test first if we believe that a woman may have, or be at risk for cervical cancer," said Dr. Wafic ElMasri, gynecologic oncology specialist at Community Physician Network. "This is one more option to help us detect and prevent cervical cancer."

ElMasri also states that approval by the FDA means that the test is safe.

"This approval for primary testing means that the HPV test is safe and effective in screening for cervical cancer based on evidence from clinical trials (notably, the ATHENA Trial). The ATHENA trial found that nearly 1 in 7 women who had a normal Pap test and were later found to have a certain type of HPV actually had high-grade cervical precancerous lesions."

However, it is important to note that this test does not replace the Pap test.

"The FDA approval doesn’t mean the HPV test must or should be used first," said ElMasri. "The HPV test does not replace the Pap test. National medical organizations, like The Society of Gynecologic Oncologists, are working on developing new guidelines that will incorporate HPV testing in current cervical cancer screenings."

For more information about current Pap testing visit www.womenshealth.gov or call a Community expert at 800.777.7775.


Women with BRCA mutations should remove ovaries

Written by Community Health Network on 2/27/2014 7:00:00 PM

A recent study published in the Journal of Clinical Oncology studied nearly 5,800 women with specific genetic mutations called BRCA1 and BRCA2.

Researchers found that women with BRCA1 and BRCA2 mutations who proactively had their ovaries removed reduced their risk of ovarian, fallopian tube, or peritoneal cancer by 80 percent, and their overall risk of death by 77 percent.

BRCA stands for breast cancer susceptibility genes, a class of genes that are tumor suppressors. Mutations of the BRCA1 and BRCA2 genes have been linked to hereditary breast and ovarian cancer.

According to the study, women with BRCA1 mutations should have preventive ovarian surgery (known as prophylactic oophorectomy) by age 35, because waiting past that age is shown to increase the risk of ovarian cancer.

In contrast, the study suggests that women with BRCA2 mutations can delay surgery until their 40s, as their risk of ovarian cancer is not as high.

Dr. Wafic ElMasri, ovarian cancer specialist"Patients with BRCA mutations are at high risk of developing ovarian cancer, which is usually diagnosed at advanced stages and is lethal in the majority of cases," said Dr. Wafic ElMasri, OB/GYN and gynecological oncologist at Community Health Network.

"We do not have reliable screening tests that detect ovarian cancer at early stages," said ElMasri. "BRCA mutation carriers should undergo risk-reducing removal of the fallopian tubes and ovaries between ages 35 and 40, or when childbearing is complete." 

How do I know if I have a BRCA gene mutation?

To determine if you carry the hereditary gene, know your family history. If there is a first or second degree connection to breast or ovarian cancer in the family, your risk for being diagnosed with cancer is increased. You can then have a genetic test performed to determine if you do, in fact, have the gene mutation.

Where can I get genetic testing?

Community Health Network provides genetic testing and counseling for women who believe that they are at risk for developing cancer. To learn more, or to schedule a test, call 317-621-8988.


Viewing 1-2 of 2 result(s).

Appointments available!

To make an appointment with an MD Anderson Cancer Network® certified physician at Community, call 800-777-7775 today!



Meet our nurse navigators

When it comes to your fight against cancer, they've got your back. Our nurse navigators act as a guide, resource, advocate and educator for newly diagnosed cancer patients and their families. Learn more here.


Categories


Tags